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hrp0082p1-d2-118 | Fat Metabolism & Obesity (1) | ESPE2014

Plasminogen Activator Inhibitor-1(Pai-1) Levels, Pai-1 Gene Polymorphism, and Family History of Cardiovascular Disease in Relation to Metabolic Parameters in a Sample of Obese Children

Karabouta Zacharoula , Makedou Areti , Argiriou Anagnostis , Papandreou Dimitrios , Xanthopoulou Eleni , Bisbinas Vasiliki , Athanassiadou-Piperopoulou Fani , Rousso Israel

Background: Obesity is a metabolic disorder associated with increased PAI-1 levels in the circulation. This increase is related to insulin resistance and cardiovascular disease (CVD). In adults the relationship between plasma PAI-1 levels and the 4G/5G gene polymorphism in the PAI-1 gene has been demonstrated, but few data exist in children.Objective and hypotheses: To assess the relationship between PAI-1 plasma levels and the PAI-1 4G allele gene polym...

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Plasminogen Activator Inhibitor-1(Pai-1) Levels, Pai-1 Gene Polymorphism, and Family History of Cardiovascular Disease in Relation to Metabolic Parameters in a Sample of Obese Children

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